From the category archives:

Market trends

Part of a continuing series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

What’s IBM’s Watson been up to since winning Jeopardy? Among other things, it’s been trying to help doctors make decisions. “We live in an age of information overload,” says Mike Rhodin, Senior Vice President of the IBM Watson Group. “The challenge is to now turn that information into knowledge.”

Interestingly, most of the inquiries Rhodin received post-Jeopardy were from doctors, who were interested in the way Watson sorted and ranked possible answers. Here, Rhodin and Dan Cerutti, VP of Watson Commercialization, outline IBM’s vision to improve global health care through a technology platform called CarePlex:

Stay tuned as we post more sessions from the Pediatric Innovation Summit (also available on YouTube) and read our blog coverage.

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Third in a series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

Ezekiel “Zeke” Emanuel MD, PhD, former health advisor to President Barack Obama and current Vice Provost for Global Initiatives and Chair of the Department of Medical Ethics & Health Policy at University of Pennsylvania, has plenty to say about where health care is headed. Keynoting at the Global Pediatric Summit 2014, Zeke outlines six predictions and what academic medical centers and the larger industry will need to do to survive.

Stay tuned as we post more sessions from the Pediatric Innovation Summit (also available on YouTube) and read our blog coverage.

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Monique Yoakim Turk Technology Development FundMonique Yoakim-Turk, PhD, is a partner of the Technology Development Fund and associate director of the Technology and Innovation Development Office at Boston Children’s Hospital

Since 2009, Boston Children’s Hospital has committed $6.2 million to support 58 hospital innovations ranging from therapeutics, diagnostics, medical devices and vaccines to regenerative medicine and healthcare IT projects. What a difference six years makes.

The Technology Development Fund (TDF) was proposed to Boston Children’s senior leadership in 2008 after months of research. As a catalyst fund, the TDF is designed to transform seed-stage academic technologies at the hospital into independently validated, later-stage, high-impact opportunities sought by licensees and investors. In addition to funds, investigators get access to mentors, product development experts and technical support through a network of contract research organizations and development partners. TDF also provides assistance with strategic planning, intellectual property protection, regulatory requirements and business models.

Seeking some “metrics of success” beyond licensing numbers and royalties (which can come a decade or so after a license), I asked recipients of past TDF awards to report back any successes that owed at least in part to data generated with TDF funds. While we expected some of the results, we would have never anticipated such a large impact. Full story »

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Naomi Fried, PhD, is Chief Innovation Officer at Boston Children’s Hospital.

Return on innovation ROI

When people hear about ROI, they often think of financial returns and “return on investment.” But, in my world, ROI is actually “return on innovation.” While the return on innovation can be financial, it can also take many other forms. Here are my top five. Full story »

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Judy Wang, MS, is a program manager in the Telehealth Program at Boston Children’s Hospital.

hackathons

Hackathons create ideas and excitement, but then reality sets in.

Much has been written about the successes that result from medical hackathons, in which people from across the health care ecosystem converge to solve challenges. For example, PillPack, which formed out of MIT Hacking Medicine, recently closed an $8.75 million funding round. But is this a realistic snapshot of what happens after a hackathon? We took a look at two of the 16 teams that competed at Boston Children’s Hospital’s Hacking Pediatrics last year. Full story »

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Boston Globe CRISPR gene editing research

You have an immune system. Your cat has an immune system. And bacteria have an immune system, too—one that we’ve tapped to make one of the most powerful tools ever for editing genes.

The tool is called CRISPR (for “clustered regularly interspaced short palindromic repeats”), and it makes use of enzymes that “remember” viral genes and cut them out of bacterial genomes. Applied to bioengineering, CRISPR is launching a revolution. And the Boston Globe reported over the weekend that while researchers at the University of California at Berkeley first developed CRISPR, the technique is booming in labs around Boston. Full story »

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zeke-emanuel-summit

Twenty percent of hospitals will close by the end of the decade, predicted bioethicist Ezekiel “Zeke” Emanuel MD, PhD, during a keynote address at the Boston Children’s Hospital Global Pediatric Innovation Summit + Awards.

How can hospitals make the cut and stay alive? The only way is to deliver high-quality, low-cost care that elicits patient allegiance, said Emanuel, a former health advisor to President Barack Obama, the chair of the Department of Medical Ethics & Health Policy at the University of Pennsylvania, and the author of Reinventing American Health Care. Full story »

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Rare disease panelWhen a rare disease affects you or your family, it doesn’t seem rare. Add them all up, and rare diseases aren’t all that uncommon. What’s rare is for patients to receive effective treatments.

“There are 7,000 rare diseases, and under 400 approved drugs,” says Peter Saltonstall, president and CEO of the National Organization for Rare Disorders (NORD), “so there’s a huge opportunity there to try to develop more drugs.”

Saltonstall spoke today with five other panelists at Boston Children’s Hospital’s Global Pediatric Innovation Summit + Awards in a session titled, “Rare diseases: Lessons from the path less chosen.” David Meeker, MD, president and CEO of Genzyme, moderated. Full story »

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The mobile and digital health market is evolving with great intensity and speed. The surge in wearable technology, health-related apps and the explosion of digital health communication continue to flood the marketplace.

Joseph Kvedar, MD, of Partners Healthcare’s Center for Connected Health—who took part in a think tank of panelists at Boston Children’s Hospital’s Global Pediatric Innovation Summit + Awards 2014—says this surge is the beginning of the “mHealth” revolution:

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BCH_InnoSummit14_RhodinMike-3The only machine to ever win a TV game show is now transforming the world of healthcare.

After winning Jeopardy in 2011, IBM’s Watson has moved on to bigger and better things. Mike Rhodin, Senior Vice President of the IBM Watson Group, told the audience at Boston Children’s Hospital’s Global Pediatric Innovation Summit + Awards 2014 how the cognitive computing system is being used to synthesize medical data and assist clinicians caring for complex patients.

“We live in an age of information overload,” Rhodin explained. “The challenge is to now turn that information into knowledge.” Full story »

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